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Quick Details

  • Type: Herbal Extract
  • Variety: Other
  • Form: Powder
  • Part: Other
  • Extraction Type: Solvent Extraction
  • Packaging: Drum
  • Place of Origin: China (Mainland)
  • Grade: Food Grade and Pharmaceutical Grade
  • Brand Name: Plamed
  • Model Number: PM0038
  • Product Name: Nattokinase Powder
  • Botanical Source: Glycine max (L.)Merr
  • Sample: Free
  • Usage: Pharmaceutical, cosmetic and food
  • Specification: Nattokinase 12000FU/G, 20000FU/G
  • Standard: In house,USP,JP,EP,BP
  • Color: Yellow-white
  • Appearance: Yellow-white fine powder
  • Test: HPLC
  • Supplier: Plamed Green Science Group

Packaging & Delivery

Packaging Details 25kgs/drum, inner by double plastic bag, 1~20kg by aluminum foil vacuum bag.
Delivery Time 3-5 working days after receiving payment

Buy Nattokinase Powder

1.Product name: Nattokinase Powder

2.Color: Light yellow fine powder

3.Source: Japanese Natto 

4.Test method: HPLC

5.Active ingredient: Nattokinase

6.CAS: 133876-92-3

7.Supplier: Plamed Green Science Group


Nattokinase, a potent fibrinolytic enzyme, is one of many enzymes derived from a popular Japanese food called natto. It has been found to have blood clot dissolving abilities and prevents the aggregation of red blood cells. It is used to make anti-clotting medicine.

About the measurement (fu/g): The potency of nattokinase is often measured by the enzyme’s ability to degrade fibrin over a given amount of time, and is represented by Fibrinolytic Units.

 Natto is a traditional Japanese fermented soybean dish and dietary staple that has been used in Japanese culture for more than 1,000 years for its popular taste. Natto is simple to make, requiring only soybeans, straw and water. Steamed beans are mixed with straw, which contains the bacteria Bacillus subtilis, and left to ferment for 24 hours. The resulting product is sticky and has a stringy, web-like consistency. It has been used as a folk remedy for heart and vascular diseases.







Nattokinase 5000FU/g, 20000FU/g



White Fine Powder




Natto (Fermented soybeans)

Physical Characteristics

Partical size

95%Through 80 Mesh

Loss on Drying


Vitamin K2


Soy Isoflavone





Water Soluble

Heavy Metals

Total Heavy Metals






Microbiological Tests

Total Plate Count


Total Yeast & Mold








Anti-clotting and Fibrinolysis

Nattokinase exhibits direct fibrinolytic properties that may degrade fibrin and reduce the risk of cardiovascular complications. This direct activity is lost upon destruction of the enzyme (heat treatment or digestion), but the peptides from nattokinase appear to increase levels of plasminogen activator which also has a fibrinolytic effect indirectly. The fibrinolytic activity of nattokinase is reportedly 4 times that of plasmin.

High blood pressure

Research suggests that prolonged supplementation (about 8 weeks) of nattokinase daily can reduce systolic and diastolic blood pressure in people with mildly high blood pressure. Nattokinase appears to exert mixed-type inhibition on the Angiotensin Converting Enzyme, and this is thought to be related not to enzyme activity but due to bioactive peptides from nattokinase. The byproducts of enzyme digestion (when the enzyme nattokinase is destroyed) appear to be bioactive dipeptides and tripeptides, which have ACE inhibitory potential or may otherwise reduce blood pressure

Deep vein thrombosis (DVT)

Nattokinase can be used for the prevention of deep vein thrombosis (DVT) during long airline flights (7-8 hours). Nattokinase, in combination with pycnogenol, was reported to decrease the chance of getting a blood clot in the legs determined by ultrasound of the venous system during long flights. Edema scores were also reduced, possibly due to the diuretic effect of pycnogenol.

2000FU-6000FU daily, taken with meals is recommended.


           Water Solubility 

Recommended Dosage for different specification


Recommended Dosage








Medical and health industry

Soft gel capsules; hard shell capsules; tablets

cardiovascular health

Food industry

Functional food

Cardiovascular health

Flow Chart: 








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